Intravenous Fluid Challenge Decreases Intracellular Volume: A Bioimpedance Spectroscopy-Based Crossover Study in Healthy Volunteers
نویسندگان
چکیده
منابع مشابه
Segment-specific resistivity improves body fluid volume estimates from bioimpedance spectroscopy in hemodialysis patients.
Discrepancies in body fluid estimates between segmental bioimpedance spectroscopy (SBIS) and gold-standard methods may be due to the use of a uniform value of tissue resistivity to compute extracellular fluid volume (ECV) and intracellular fluid volume (ICV). Discrepancies may also arise from the exclusion of fluid volumes of hands, feet, neck, and head from measurements due to electrode positi...
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PURPOSE Estimation of body fluid volume in hyponatremia is useful for diagnosis and therapeutic decision-making. Physical examination has been generally used to estimate body fluid volume, but it depends on the physician's abilities. Bioimpedance spectroscopy has been suggested to be a reliable method for the estimation of body fluid volume. Therefore, this study investigated whether bioimpedan...
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BACKGROUND Cannabidiol (CBD) is a nonpsychoactive phytocannabinoid used in multiple sclerosis and intractable epilepsies. Preclinical studies show CBD has numerous cardiovascular benefits, including a reduced blood pressure (BP) response to stress. The aim of this study was to investigate if CBD reduces BP in humans. METHODS Nine healthy male volunteers were given 600 mg of CBD or placebo in ...
متن کاملAlterations in coagulation and fibrinolysis after levothyroxine exposure in healthy volunteers: a controlled randomized crossover study.
BACKGROUND Several hemostatic abnormalities have been reported in hyperthyroidism, but the overall effect of thyroid hormone excess on coagulation and fibrinolysis is unclear. OBJECTIVE Our aim was to assess whether the use of supraphysiological doses of levothyroxine leads to coagulation activation and inhibition of fibrinolysis. PATIENTS AND METHODS Healthy volunteers were randomized to r...
متن کاملBioimpedance Spectroscopy
In the context of biology, electrical phenomena are usually identified with ionic currents through protein channels, for example as they are postulated during nerve signalling (Andersen et al. Prog Neurobiol 88(2):104–113, 2009; Sakmann and Neher Annu Rev Physiol 46:455–472, 1984). However, there are more electrical phenomena that play a significant role in biological systems, namely those aris...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/s41598-017-09433-5